Toll樣受體4(TLR4)重組蛋白
Recombinant Toll Like Receptor 4 (TLR4)
CD284; TOLL; HToll
- 編號(hào)RPA753Hu01
- 物種Homo sapiens (Human，人)相同的名稱，不同的物種。
- 來(lái)源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位細(xì)胞膜
- 預(yù)測(cè)分子量42.0kDa
- 實(shí)際分子量40kDa(差異分析請(qǐng)參閱說(shuō)明書)
- 片段與標(biāo)簽Phe326~Ile634 with N-terminal His Tag
- 緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性狀凍干粉
- 純度> 80%
- 等電點(diǎn)5.8
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見(jiàn)活性蛋白。 - 下載英文說(shuō)明書 中文說(shuō)明書
- 規(guī)格10μg50μg200μg1mg5mg
- 價(jià)格¥ 864¥ 2160¥ 4320¥ 12960¥ 32400
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Figure. Gene Sequencing (Extract)
Figure. SDS-PAGE
通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPA753Hu01 | Toll樣受體4(TLR4)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA753Hu01 | Toll樣受體4(TLR4)活性蛋白 | Cell?culture;?Activity?Assays. |
| APA753Hu02 | Toll樣受體4(TLR4)活性蛋白 | Cell?culture;?Activity?Assays. |
| RPA753Hu02 | Toll樣受體4(TLR4)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA753Hu03 | Toll樣受體4(TLR4)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA753Hu04 | Toll樣受體4(TLR4)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| CPA753Hu21 | Toll樣受體4(TLR4)卵白蛋白偶聯(lián)物 | Immunogen; SDS-PAGE; WB. |
| PAA753Hu02 | Toll樣受體4(TLR4)多克隆抗體 | IHC |
| PAA753Hu01 | Toll樣受體4(TLR4)多克隆抗體 | WB; FCM |
| PAA753Hu08 | Toll樣受體4(TLR4)多克隆抗體 | WB; IHC; ICC; IP. |
| LAA753Hu71 | Toll樣受體4(TLR4)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| MAA753Hu25 | Toll樣受體4(TLR4)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA753Hu24 | Toll樣受體4(TLR4)單克隆抗體 | WB |
| MAA753Hu23 | Toll樣受體4(TLR4)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA753Hu21 | Toll樣受體4(TLR4)單克隆抗體 | WB |
| MAA753Hu22 | Toll樣受體4(TLR4)單克隆抗體 | WB |
| LAA753Hu72 | Toll樣受體4(TLR4)單克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| MEA753Hu | Toll樣受體4(TLR4)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法,小樣本) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SEA753Hu | Toll樣受體4(TLR4)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA753Hu | Toll樣受體4(TLR4)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| PSA753Hu01 | Toll樣受體4(TLR4)抗體對(duì) | ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays. |
| KSA753Hu01 | Toll樣受體4(TLR4)檢測(cè)試劑盒DIY材料(酶聯(lián)免疫吸附試驗(yàn)法) | Main materials for "Do It (ELISA Kit) Yourself". |
參考文獻(xiàn)
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| Journal For?Neurovirology | Soluble?TLR2?and?4?concentrations?in?cerebrospinal?fluid?in?HIV/SIV-relatedneuropathological?conditions.[pubmed:27882497] |
| Acta?Orthopaedica | Toll-like receptors and their soluble forms differ in the knee and thumb basal osteoarthritic joints[pubmed:28093922] |
| Environmental Toxicology and Pharmacology | Ameliorative potential of linagliptin and/or calcipotriol on bleomycin-induced lung fibrosis: In vivo and in vitro study[pubmed:28192751] |
| Inflammation | Toll-Like Receptor 4 Inhibition Improves Oxidative Stress and Mitochondrial Health in Isoproterenol-Induced Cardiac Hypertrophy in Rats[pubmed:28690610] |
| Comparative Immunology, Microbiology and Infectious Diseases | Probiotic Lactobacillus acidophilus bacteria or synthetic TLR2 agonist boost the growth of chicken embryo intestinal organoids in cultures comprising epithelial cells and myofibroblasts[DOI: 10.1016/j.cimid.2017.06.002] |
| Comparative Immunology, Microbiology and Infectious Diseases | Probiotic Lactobacillus acidophilus bacteria or synthetic TLR2 agonist boost the growth of chicken embryo intestinal organoids in cultures comprising epithelial cells and myofibroblasts[10.1016/j.cimid.2017.06.002] |
| Microbial Pathogenesis | Protective effects of sinomenine against LPS-induced inflammation in piglets.[pubmed:28757275] |
| Cytokine | Soy isoflavone genistein attenuates lipopolysaccharide-induced cognitive impairments in the rat via exerting anti-oxidative and anti-inflammatory effects[pubmed:29102164] |
| Biomedicine & pharmacotherapy | Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms[pubmed:28061403] |
| Frontiers in Immunology | The soluble Form of Toll-like receptor 2 is elevated in serum of Multiple sclerosis Patients: a novel Potential Disease Biomarker[Pubmed:29593720] |
| Experimental Gerontology | Specific alterations in the circulating levels of the SIRT1, TLR4, and IL7 proteins in patients with dementia[Pubmed:30071285] |
| Neurotoxicity Research | Protective Effects of Fibroblast Growth Factor 21 Against Amyloid-Beta-Induced Toxicity in SH-SY5Y Cells[Pubmed:29869772] |
| European?Journal of Pharmacology | Rutin, a quercetin glycoside, alleviates acute endotoxemic kidney injury in C57BL/6 mice via suppression of inflammation and up-regulation of antioxidants and SIRT1[Pubmed:29920283] |
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| Physiology &?Behavior? | Linagliptin potentiates the effect of l-dopa on the behavioural, biochemical and immunohistochemical changes in experimentally-induced Parkinsonism: Role of toll?…[Pubmed:29410018] |
| International Journal of Gynecology & Obstetrics | Increased serum levels of high mobility group protein B1 and calprotectin in pre‐eclampsia[Pubmed:29569400] |
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| ТLR4-Р?ВН? У ХВОРИХ НА ПОДАГРУ: ЗВ'ЯЗОК З АКТИВН?СТЮ ЗАХВОРЮВАННЯ[:] | |
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| Immunopharmacology?and?immunotoxicology | Protective effect of sesamin in lipopolysaccharide-induced mouse model of acute kidney injury via attenuation of oxidative stress, inflammation, and apoptosis[Pubmed: 30488751] |
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| Biomedicine?& Pharmacotherapy | Opuntioside, opuntiol and its metallic nanoparticles attenuate adjuvant-induced arthritis: Novel suppressors of Toll-like receptors-2 and-4[] |
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| Scientific Reports | Deregulation of TLR4 signaling pathway characterizes Bicuspid Aortic valve syndrome[Pubmed: 31363123] |
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| The role of Toll-like receptors-4 in the pathogenesis of development of anemia of inflammation in young children[] | |
| Clin Oral Investig | Evaluation of heat shock protein 70 and toll-like receptor 4 expression in gingival crevicular fluid in response to orthodontic forces[34091792] |
| Eksp Klin Gastroenterol | Tissue transglutaminase is involved in the inflammatory processes of active chronic gastritis[17539352] |
| Iranian Journal of Medical Sciences | Esculetin Alleviates Acute Liver Failure following Lipopolysaccharide/D-Galactosamine in Male C57BL/6 Mice[] |
| Acta Obstet Gynecol Scand | A value of soluble Toll‐like receptor 2 and 4 in vaginally obtained amniotic fluid for the prediction of histological chorioamnionitis[34244993] |
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| Frontiers in Pharmacology | Carbocisteine as a Modulator of Nrf2/HO-1 and NFκB Interplay in Rats: New Inspiration for the Revival of an Old Drug for Treating Ulcerative Colitis. Front?…[Pubmed:35754464] |
| Processes | Lipocalin, Resistin and Gut Microbiota-Derived Propionate Could Be Used to Predict Metabolic Bariatric Surgery Selected Outcomes[] |
| Biomolecules | Vascular Calcification and the Gut and Blood Microbiome in Chronic Kidney Disease Patients on Peritoneal Dialysis: A Pilot Study[] |