α-黑素細(xì)胞刺激素(aMSH)合成多肽
Synthetic Alpha-Melanocyte Stimulating Hormone (aMSH)
α-MSH; Intermedins; Alpha-Melanotropin, Alpha-Melanocortin; Alpha-Intermedin
- 編號SPA239Mi01
- 物種Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Oryctolagus cuniculus (Rabbit，兔), Sus scrofa; Porcine (Pig，豬), Bos taurus; Bovine (Cattle，牛), Ovis aries; Ovine (Sheep，綿羊)相同的名稱，不同的物種。
- 來源多肽合成
- 預(yù)測分子量-
- 緩沖液成份磷酸鹽緩沖液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性狀凍干粉
- 純度> 90%
- 等電點-
- 應(yīng)用Immunogen; Blocking Peptide.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載英文說明書 中文說明書
- 規(guī)格10μg50μg200μg1mg5mg
- 價格¥ 840¥ 2100¥ 4200¥ 12600¥ 31500
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Figure. MASS Spectrometry of the Original Peptide
Figure. HPLC of the Original Peptide
通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
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相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Oryctolagus cuniculus (Rabbit，兔), Sus scrofa; Porcine (Pig，豬), Bos taurus; Bovine (Cattle，牛), Ovis aries; Ovine (Sheep，綿羊) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| CPA239Mi21 | α-黑素細(xì)胞刺激素(aMSH)卵白蛋白偶聯(lián)物 | Immunogen; SDS-PAGE; WB. |
| SPA239Mi01 | α-黑素細(xì)胞刺激素(aMSH)合成多肽 | Immunogen; Blocking Peptide. |
| PAA239Mi08 | α-黑素細(xì)胞刺激素(aMSH)多克隆抗體 | IHC |
| MAA239Mi21 | α-黑素細(xì)胞刺激素(aMSH)單克隆抗體 | IHC |
| MAA239Mi22 | α-黑素細(xì)胞刺激素(aMSH)單克隆抗體 | IHC |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| J Biochem. | Generation of a human bone marrow-derived mesenchymal stem cell line expressing and secreting high levels of bioactive α-melanocyte-stimulating hormone.[Pubmed: 23341471] |
| Pigment Cell Melanoma Res | Pharmacological induction of skin pigmentation unveils the neuroendocrine circuit regulated by light[PubMed: 26582755] |
| The Journal of Biological Chemistry | Intermedin Restores Hyperhomocysteinemia-induced Macrophage Polarization and Improves Insulin Resistance in Mice[Pubmed:27080257] |
| Pigment Cell & Melanoma Research | Pharmacological induction of skin pigmentation unveils the neuroendocrine circuit reCavia (Guinea pig )lated by light[Pubmed:26582755] |
| Nature Communications | Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives.[pubmed:28794470] |
| Cell?Stem?Cell | Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses[Pubmed:29681516] |
| European Neuropsychopharmacology | Epigenetic alterations of the POMC promoter in tobacco dependence[Pubmed:29871818] |
| Neuropeptides | Mechanisms of sustained long-term weight loss after RYGB: α-MSH is a key factor[Pubmed:29685637] |
| Neuropsychobiology | Alcohol Withdrawal and Proopiomelanocortin Neuropeptides in an Animal Model of Alcohol Dependence[Pubmed: 31117084] |
| INTERNATIONAL IMMUNOPHARMACOLOGY | Intermedin alleviates the inflammatory response and stabilizes the endothelial barrier in LPS-induced ARDS through the PI3K/Akt/eNOS signaling pathway[Pubmed: 32892076] |
| J Endocrinol Invest | Serum alpha-melanocyte-stimulating hormone (a-MSH), brain-derived neurotrophic factor (BDNF), and agouti-related protein (AGRP) levels in children with Prader?…[Pubmed:35098494] |