α-黑素細(xì)胞刺激素(aMSH)多克隆抗體
Polyclonal Antibody to Alpha-Melanocyte Stimulating Hormone (aMSH)
α-MSH; Intermedins; Alpha-Melanotropin, Alpha-Melanocortin; Alpha-Intermedin
- 編號(hào)PAA239Mi08
- 物種Homo sapiens (Human,人), Mus musculus (Mouse,小鼠), Rattus norvegicus (Rat,大鼠), Oryctolagus cuniculus (Rabbit,兔), Sus scrofa; Porcine (Pig,豬), Bos taurus; Bovine (Cattle,牛), Ovis aries; Ovine (Sheep,綿羊)相同的名稱(chēng),不同的物種。
- 來(lái)源多抗制備
- 宿主兔
- 效價(jià)-
- Ig類(lèi)型IgG
- 純化方式抗原特異性親和純化
- 標(biāo)記物無(wú)標(biāo)記物
- 免疫原CPA239Mi21-α-黑素細(xì)胞刺激素(aMSH)卵白蛋白偶聯(lián)物
- 緩沖液成份0.01M 磷酸鹽緩沖液(pH7.4,containing 0.05% Proclin-300,50% glycerol)
- 性狀液體
- 濃度0.5mg/mL
- 且適物種Sus scrofa; Porcine (Pig,豬)
- 應(yīng)用IHC
如果抗體需用于流式細(xì)胞術(shù),請(qǐng)參見(jiàn)流式抗體。 - 下載英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格20μl100μl200μl1ml10ml
- 價(jià)格¥ 616 ¥ 1436¥ 2052¥ 5130¥ 20520
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特異性
該抗體是針對(duì)aMSH的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識(shí)別aMSH。
用法
Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲(chǔ)存
經(jīng)常使用則4°C保存。-20°C保存不超過(guò)兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定,具體方法如下:在37°C孵育48小時(shí),沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲(chǔ),損失率低于5%。
贈(zèng)品
增值服務(wù)
相關(guān)產(chǎn)品
編號(hào) | 適用物種:Homo sapiens (Human,人), Mus musculus (Mouse,小鼠), Rattus norvegicus (Rat,大鼠), Oryctolagus cuniculus (Rabbit,兔), Sus scrofa; Porcine (Pig,豬), Bos taurus; Bovine (Cattle,牛), Ovis aries; Ovine (Sheep,綿羊) | 應(yīng)用(僅供研究使用,不用于臨床診斷!) |
CPA239Mi21 | α-黑素細(xì)胞刺激素(aMSH)卵白蛋白偶聯(lián)物 | Immunogen; SDS-PAGE; WB. |
SPA239Mi01 | α-黑素細(xì)胞刺激素(aMSH)合成多肽 | Immunogen; Blocking Peptide. |
PAA239Mi08 | α-黑素細(xì)胞刺激素(aMSH)多克隆抗體 | IHC |
MAA239Mi21 | α-黑素細(xì)胞刺激素(aMSH)單克隆抗體 | IHC |
MAA239Mi22 | α-黑素細(xì)胞刺激素(aMSH)單克隆抗體 | IHC |
參考文獻(xiàn)
雜志 | 參考文獻(xiàn) |
J Biochem. | Generation of a human bone marrow-derived mesenchymal stem cell line expressing and secreting high levels of bioactive α-melanocyte-stimulating hormone.[Pubmed: 23341471] |
Pigment Cell Melanoma Res | Pharmacological induction of skin pigmentation unveils the neuroendocrine circuit regulated by light[PubMed: 26582755] |
The Journal of Biological Chemistry | Intermedin Restores Hyperhomocysteinemia-induced Macrophage Polarization and Improves Insulin Resistance in Mice[Pubmed:27080257] |
Pigment Cell & Melanoma Research | Pharmacological induction of skin pigmentation unveils the neuroendocrine circuit reCavia (Guinea pig )lated by light[Pubmed:26582755] |
Nature Communications | Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives.[pubmed:28794470] |
Cell?Stem?Cell | Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses[Pubmed:29681516] |
European Neuropsychopharmacology | Epigenetic alterations of the POMC promoter in tobacco dependence[Pubmed:29871818] |
Neuropeptides | Mechanisms of sustained long-term weight loss after RYGB: α-MSH is a key factor[Pubmed:29685637] |
Neuropsychobiology | Alcohol Withdrawal and Proopiomelanocortin Neuropeptides in an Animal Model of Alcohol Dependence[Pubmed: 31117084] |
INTERNATIONAL IMMUNOPHARMACOLOGY | Intermedin alleviates the inflammatory response and stabilizes the endothelial barrier in LPS-induced ARDS through the PI3K/Akt/eNOS signaling pathway[Pubmed: 32892076] |
J Endocrinol Invest | Serum alpha-melanocyte-stimulating hormone (a-MSH), brain-derived neurotrophic factor (BDNF), and agouti-related protein (AGRP) levels in children with Prader?…[Pubmed:35098494] |