內(nèi)皮型一氧化氮合酶(eNOS)重組蛋白
Recombinant Endothelial NOS (eNOS)
NOS3; ECNOS; NOS III; E-NOS; C-NOS; ENOS; CNOS; Constitutive NOS; Nitric Oxide Synthase 3, Endothelial
- 編號RPA868Hu01
- 物種Homo sapiens (Human，人)相同的名稱，不同的物種。
- 來源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細(xì)胞定位細(xì)胞膜, 細(xì)胞質(zhì)
- 預(yù)測分子量15.8kDa
- 實(shí)際分子量19kDa(差異分析請參閱說明書)
- 片段與標(biāo)簽Arg756~Gln888 with N-terminal His Tag
- 緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性狀凍干粉
- 純度> 97%
- 等電點(diǎn)6.4
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載英文說明書 中文說明書
- 規(guī)格10μg50μg200μg1mg5mg
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Figure . Gene Sequencing (extract)
Figure. SDS-PAGE
通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| APA868Hu01 | 內(nèi)皮型一氧化氮合酶(eNOS)活性蛋白 | Cell?culture;?Activity?Assays. |
| RPA868Hu03 | 內(nèi)皮型一氧化氮合酶(eNOS)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA868Hu04 | 內(nèi)皮型一氧化氮合酶(eNOS)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA868Hu01 | 內(nèi)皮型一氧化氮合酶(eNOS)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA868Hu04 | 內(nèi)皮型一氧化氮合酶(eNOS)多克隆抗體 | WB; IHC; ICC; IP. |
| PAA868Hu03 | 內(nèi)皮型一氧化氮合酶(eNOS)多克隆抗體 | WB; IHC; ICC; IP. |
| PAA868Hu01 | 內(nèi)皮型一氧化氮合酶(eNOS)多克隆抗體 | WB; IHC |
| LAA868Hu71 | 內(nèi)皮型一氧化氮合酶(eNOS)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| MAA868Hu22 | 內(nèi)皮型一氧化氮合酶(eNOS)單克隆抗體 | WB; IHC; ICC; IP. |
| SEA868Hu | 內(nèi)皮型一氧化氮合酶(eNOS)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA868Hu | 內(nèi)皮型一氧化氮合酶(eNOS)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Journal of Ethnopharmacology | Impact of matrine on inflammation related factors in rat intestinal microvascular endothelial cells[ScienceDirect: S0378874109004541] |
| PLoS One | A Novel Mechanism of Formaldehyde Neurotoxicity: Inhibition of Hydrogen Sulfide Generation by Promoting Overproduction of Nitric Oxide[PubMed: 23359814] |
| 6th International Scientific Interdisciplinary Conference (ISIC) | Inflammation influence on the formation of endothelial dysfunction in hypertensive patients caused by obesity[Knmu: Source] |
| PLoS One. | SIRT1 Gene Polymorphisms Affect the Protein Expression in Cardiovascular Diseases[Plos: Source] |
| INTERNATIONAL JOURNAL OF MEDICINE AND MEDICAL RESEARCH | L-ARGININE, BUT NOT L-NAME PROTECTS AGAINST LIVER INJURY INDUCED BY EXPERIMENTAL ISCHEMIA-REPERFUSION[Tdmu:Source] |
| Journal of Clinical Laboratory Analysis | Soluble Lectin-Like Oxidized LDL Receptor 1 as a Possible Mediator of Endothelial Dysfunction in Patients With Metabolic Syndrome[Pubmed:24798146] |
| Endocrine | Chemerin plays a protective role by regulating human umbilical vein endothelial cell-induced nitric oxide signaling in preeclampsia[Pubmed:24840719] |
| PLOS ONE | A Remarkable Age-Related Increase in SIRT1 Protein Expression against Oxidative Stress in Elderly:[PubMed: 25785999] |
| J Trace Elem Med Biol | Comparative angioprotective effects of magnesium compounds[PubMed: 25127069] |
| Journal of Functional Foods | Peptides from hydrolysate of lantern fish (Benthosema pterotum) proved neuroprotective in vitro and in vivo[science:S1756464616300639] |
| Медицина и здравоохранение | Роль индуцибельной NO-синтазы в механизмах регуляции функциональной активности кальций-активируемых калиевых каналов коронарных сосудов у крыс, адаптированных к стрессу[article:n] |
| journal of molecular and cellular cardiology | Mutant DD genotype of NFKB1 gene is associated with the susceptibility and severity of coronary artery disease.[pubmed:28088561] |
| International Journal of Medicine and Medical Research | ThE REmOdELINg Of LEfT ATRIUm ANd vAsOdILATION fAcTORs chANgEs IN IschEmIc hEART fAILURE[7038] |
| International Journal of Ophthalmology | Endothelial?nitric?oxide?synthase?deficiency?influences?normal?cell?cycle?progression?andapoptosis?in?trabecular?meshwork?cells.[pubmed:27366677] |
| Biomed Pharmacother. | SIRT1 inhibits releases of HMGB1 and HSP70 from human umbilical vein endothelial cells caused by IL-6 and the serum from a preeclampsia patient and protects the cells from death.[pubmed:28122311] |
| Biomedicine & Pharmacotherapy | SIRT1 inhibits releases of HMGB1 and HSP70 from human umbilical vein endothelial cells caused by IL-6 and the serum from a preeclampsia patient and protects the cells from death[DOI:10.1016/j.biopha.2017.01.087] |
| Asian Journal of Science and Technology | THE INFLUENCE OF THE ADDITIONAL USAGE OF L-ARGININE ON THE FACTORS OF VASODILATION AND THE CLINICAL DATA, COMPLICATED WITH CARDIAC DECOMPENSATION WITH REDUCED AND PRESERVED FRACTURE OF THE LEFT VENTRICLE THAT PATIENTS WITH STABLE CORONARY HEART DISEASE HAVE[ISSN: 0976-3376] |
| National Science Review | Blunted Nitric Oxide Regulation in Tibetans under High Altitude Hypoxia[10.1093:nsr] |
| Biomedicine & Pharmacotherapy | Molecular basis of vascular damage caused by cigarette smoke exposure and a new approach to the treatment: Alpha-linolenic acid[Pubmed:29579706] |
| Experimental and Therapeutic?Medicine | Ergothioneine prevents endothelial dysfunction induced by mercury chloride[Pubmed:29805489] |
| Turk Kardiyol Dern Ars.? | Effect of statins on sirtuin 1 and endothelial nitric oxide synthase expression in young patients with a history of premature myocardial infarction[Pubmed:29664427] |
| St??enia ?ródb?onkowej i indukowalnej formy syntazy tlenku azotu w surowicy krwi kobiet ci??arnych pal?cych tytoń–badania wst?pne[] | |
| The?Eurasian?Journal of Medicine | Tadalafil Preserves Penile Nitric Oxide Synthase from Detrimental Effect of Paroxetine in Rats[Doi: 10.5152/eurasianjmed.2018.18160] |
| International Journal of Environmental Research and?Public?Health | Influence of Active Exposure to Tobacco Smoke on Nitric Oxide Status of Pregnant Women[Pubmed: 30513890] |
| Journal?of?Physics?D: Applied?Physics | Premature Myocardial Infarction: Genetic Variations in SIRT1 Affect Disease Susceptibility[] |
| Particle and?Fibre?Toxicology | Silica nanoparticles trigger the vascular endothelial dysfunction and prethrombotic state via miR-451 directly regulating the IL6R signaling pathway[Pubmed: 30975181] |
| ВЛИЯНИЕ ИНДУЦИБЕЛЬНОЙ NO-СИНТАЗЫ НА ТОНУС КОРОНАРНЫХ СОСУДОВ, СОКРАТИТЕЛЬНУЮ ФУНКЦИЮ МИОКАРДА И МЕХАНИЗМЫ?…[] | |
| Динамика показателей эндотелиальной дисфункции до и после операции у больных варикозной болезнью нижних конечностей[] | |
| European Journal of?Pharmacology | The placental growth factor attenuates intimal hyperplasia in vein grafts by improving endothelial dysfunction[Pubmed: 31836533] |
| Rheumatol Int | Circadian fluctuations of endothelial nitric oxide synthase activity in females with rheumatoid arthritis: a pilot study[Pubmed: 32025851] |
| Reviews on Recent Clinical Trials | Circadian rhythms of endothelial nitric oxide synthase and toll-like receptors 2 production in females with rheumatoid arthritis depending on NOS3 gene polymorphism?…[Pubmed: 32297585] |
| Georgian medical news | ASSOCIATIONS BETWEEN EFFICACY OF THE THERAPY AND CIRCADIAN FLUCTUATIONS OF ENDOTHELIAL NITRIC OXIDE SYNTHASE WITH TOLL-LIKE?…[Pubmed: 32242853] |
| Zaporozhye medical journal | Dynamics of endothelial dysfunction indices before and after operation in patients with varicose disease of the lower extremities[] |
| regional hemodynamics and microcirculation | Benzimidazole Derivative, 2-ETH Prevents Poststressor Disorders of Coronary Vascular Tone and Myocardial Contractility[] |
| Оксидативный стресс и эндотелиальная дисфункция в развитии экспериментального радиоиндуцированного повреждения легких и их коррекция?…[] | |
| Reprod Biol | Angiogenic factors measured in aspirated placental tissue between the 10+ 6 and 18+ 3 weeks of gestation[34798517] |
| J Basic Clin Physiol Pharmacol | Anti-atherosclerotic activity of aqueous extract of Ipomoea batatas (L.) leaves in high-fat diet-induced atherosclerosis model rats[Pubmed:34986543] |
| Eur Rev Med Pharmacol Sci | Serum inducible and endothelial nitric oxide synthase in coronary artery disease patients with Type 2 Diabetes mellitus[Pubmed:35647851] |
| Evidence-Based Complementary and Alternative Medicine | Mechanism of Fructus Mume Pills Underlying Their Protective Effects in Rats with Acetic Acid-Inducedulcerative Colitis via the Regulation of Inflammatory?…[Pubmed:35620404] |