突觸核蛋白α(SNCa)單克隆抗體

Monoclonal Antibody to Synuclein Alpha (SNCa)

SNC-A; aSYN; PD1; PARK1; PARK4; NACP; Non-A Beta Component Of Alzheimer's Disease Amyloid Precursor Protein; Non-A4 component of amyloid precursor

  • 突觸核蛋白α(SNCa)單克隆抗體產品包裝(模擬)
  • 突觸核蛋白α(SNCa)單克隆抗體產品包裝(模擬)
  • Certificate通過ISO 9001、ISO 13485質量體系認證

特異性

該抗體是針對SNCa的小鼠單克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別SNCa。

用法

免疫印跡：0.2-2μg/mL;1:500-5000
免疫組織化學：5-20μg/mL;1:50-200
免疫細胞化學：5-20μg/mL;1:50-200
最佳稀釋倍數最終由用戶決定。

儲存

經常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當的條件下存儲，損失率低于5%。

贈品

相關產品

編號適用物種：Rattus norvegicus (Rat，大鼠)應用(僅供研究使用，不用于臨床診斷！)
RPB222Ra01突觸核蛋白α(SNCa)重組蛋白Positive Control; Immunogen; SDS-PAGE; WB.
PAB222Ra01突觸核蛋白α(SNCa)多克隆抗體IHC
MAB222Ra21突觸核蛋白α(SNCa)單克隆抗體WB; IHC; ICC; IP.
SEB222Ra突觸核蛋白α(SNCa)檢測試劑盒(酶聯免疫吸附試驗法)Enzyme-linked immunosorbent assay for Antigen Detection.
LMB222Ra突觸核蛋白α(SNCa)等多因子檢測試劑盒(流式熒光發(fā)光法)FLIA Kit for Antigen Detection.
KSB222Ra01突觸核蛋白α(SNCa)檢測試劑盒DIY材料(酶聯免疫吸附試驗法)Main materials for "Do It (ELISA Kit) Yourself".

參考文獻

雜志參考文獻
The Journal of Clinical InvestigationCerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration[PubMed: PMC3428100]
Neurobiology of DiseaseLysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission[PubMed: PMC3107939]
Nature CommunicationsParkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus[PubMed: PMC3265381]
Provisional chapterMutations of PARK Genes and Alpha-Synuclein and Parkin Concentrations in Parkinson’s Disease[Intechopen:Source]
NerodegenerationApolipoprotein Eε4: A Biomarker for Executive Dysfunction among Parkinson's Disease Patients with Mild Cognitive Impairment[pubmed:29326545]
Experimental gerontologyThe anti-aging protein klotho alleviates injury of nigrostriatal dopaminergic pathway in 6-hydroxydopamine rat model of Parkinson's disease: Involvement of PKA/CaMKII/CREB signaling.[pubmed:29107062]
Neurobiology of DiseaseDevelopment and biochemical characterization of a mouse model of Parkinson's disease bearing defective glucocerebrosidase activity[Pubmed: 30521842]
molecular and cellular biochemistryPotential therapeutic effects of antagonizing adenosine A2A receptor, curcumin and niacin in rotenone-induced Parkinson's disease mice model[Pubmed: 31820278]
International Journal of PharmacologyNose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease[Pubmed: 32084576]
EBioMedicineAnti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys[Pubmed: 32810825]