骨保護素(OPG)單克隆抗體
Monoclonal Antibody to Osteoprotegerin (OPG)
TNFRSF11B; TNFRSF11-B; OCIF; OPG; TR1; Tumor Necrosis Factor Receptor Superfamily Member 11b; Osteoclastogenesis Inhibitory Factor
- 編號MAA108Ga01
 - 物種Chicken (Gallus,雞)相同的名稱,不同的物種。
 - 來源單抗制備
 - 宿主兔
 - 效價(克隆號)-
 - Ig亞型 IgG
 - 純化方式抗原特異性親和純化
 - 標記物無標記物
 - 免疫原-
 - 緩沖液成份磷酸鹽緩沖液(pH7.4,含有0.02% NaN3和50%甘油)
 - 性狀液體
 - 濃度1mg/mL
 - 且適物種-
 - 應(yīng)用WB; IHC; ICC; IP.
如果抗體需用于流式細胞術(shù),請參見流式抗體。 - 下載英文說明書 中文說明書
 - 規(guī)格20μl100μl200μl1ml10ml
 - 價格¥ 652¥ 1520¥ 2172¥ 5430¥ 21720
 - 欲了解實際交易價格和更多情況,請與當?shù)亟?jīng)銷商聯(lián)系!
 
特異性
該抗體是針對OPG的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別OPG。
用法
                        免疫印跡:0.2-2μg/mL;1:500-5000
                        
 免疫組織化學(xué):5-20μg/mL;1:50-200
                        
 免疫細胞化學(xué):5-20μg/mL;1:50-200
                        
 最佳稀釋倍數(shù)最終由用戶決定。
                        
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定,具體方法如下:在37°C孵育48小時,沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當?shù)臈l件下存儲,損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種:Chicken (Gallus,雞) | 應(yīng)用(僅供研究使用,不用于臨床診斷!) | 
| RPA108Ga01 | 骨保護素(OPG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| PAA108Ga01 | 骨保護素(OPG)多克隆抗體 | WB; IHC; ICC; IP. | 
| MAA108Ga01 | 骨保護素(OPG)單克隆抗體 | WB; IHC; ICC; IP. | 
| SEA108Ga | 骨保護素(OPG)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. | 
| LMA108Ga | 骨保護素(OPG)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. | 
參考文獻
| 雜志 | 參考文獻 | 
| Pharmacology | Protective Effect of Amlodipine on Rat Bone Tissue after Orchidectomy[Karger: 335491] | 
| Endocrine Pharmacology | Protective effect of atorvastatin on bone tissue in orchidectomised male albino Wistar rats[ScienceDirect: S0014299912000659] | 
| PLOS One | Adipokines in Psoriatic Arthritis Patients: The Correlations with Osteoclast Precursors and Bone Erosions[PubMed: PMC3483160] | 
| International Journal of Oral and Maxillofacial Surgery | The effects of chronic zoledronate usage on the jaw and long bones evaluated using RANKL and osteoprotegerin levels in an animal model[Pubmed: 23522850] | 
| American Journal of Orthodontics and Dentofacial Orthopedics | OPG and RANKL levels around miniscrew implants during orthodontic tooth movement[Pubmed: 23910201] | 
| AGE | Estrogen deficiency does not decrease the in vitro osteogenic potential of rat adipose-derived mesenchymal stem cells[Pubmed: 24687841] | 
| Food Science & Nutrition | Effects and mechanisms of 8-prenylnaringenin on osteoblast MC3T3-E1 and osteoclast-like cells RAW264.7[Onlinelibrary: fsn3.109] | 
| Food Sci Nutr. | Effects and mechanisms of 8‐prenylnaringenin on osteoblast MC3T3‐E1 and osteoclast‐like cells RAW264. 7[Pubmed:Pmc4221832] | 
| J Neurol Sci. | The effect of topiramate and lamotrigine on rat bone mass, structure and metabolism.[Pubmed:24629477] | 
| Journal of Investigative Surgery | Effect of Nicotine on RANKL and OPG and Bone Mineral Density[Pubmed:24830656] | 
| Int J Mol Med. | Effects of icariin on the regulation of the OPG?RANKL?RANK system are mediated through the MAPK pathways in IL?1β?stimulated human SW1353 chondrosarcoma …[Pubmed:25270538] | 
| Clinical and Experimental Pharmacology and Physiology | Carvedilol promotes neurological function, reduces bone loss and attenuates cell damage after acute spinal cord injury in rats[Pubmed:25424914] | 
| Journal of Colloid and Interface Science | Strontium and zoledronate hydroxyapatites graded composite coatings for bone prostheses[Pubmed:25706198] | 
| Int J Clin Exp Pathol | A novel model of bisphosphonate-related osteonecrosis of the jaw in rats[PubMed: 26191212] | 
| IJHS(international journal of health sciences) | Relation of Osteoprotegerin, Visfatin and Ghrelin to Metabolic Syndrome in Type 2 Diabetic Patients[PubMed: 26309431] | 
| Pharmacology | Effect of Mirtazapine on Rat Bone Tissue after Orchidectomy[PubMed: 25871861] | 
| Experimental And Therapeutic Medicine | Antiosteoporotic effect of icariin in ovariectomized rats is mediated via the Wnt/β-catenin pathway[Pubmed:27347050] | 
| Bone | The effects of strength training and raloxifene on bone health in aging ovariectomized rats[Pubmed:26812611] | 
| Scienze Biomediche | Effetti del laser a bassa dose su cellule osteoblastiche[INCERTIPARENTI_SERENA_TESI.pdf] | 
| journal of biomedical materials research part a | RAW 264.7 co-cultured with ultra-high molecular weight polyethylene particles spontaneously differentiate into osteoclasts: an in vitro model of periprosthetic osteolysis.[pubmed:27667508] | 
| Nutrition. | Noni leaf and black tea enhance bone regeneration in estrogen-deficient rats.[pubmed:27908549] | 
| PLoS One. | Extracorporeal shock waves alone or combined with raloxifene promote bone formation and suppress resorption in ovariectomized rats.[pubmed:28158228] | 
| Sci Rep. | Skeletal Site-specific Effects of Zoledronate on in vivo Bone Remodeling and in vitro BMSCs Osteogenic Activity.[pubmed:28139685] | 
| Journal of Biomaterials and Tissue Engineering | Modification and Characterization of Polyethylene Glycolated Decellularized Porcine Aortic Heart Valve with Osteoprotegerin[art00007] | 
| Japanese Society for Bone and Mineral Research | Allogeneic yet?major histocompatibility complex?matched bone marrow transplantation in?mice results in?an?impairment of?osteoblasts and?a?significantly reduced trabecular bone[article:10.1007] | 
| ONCOLOGY LETTERS | Assessment of bone metabolism and biomechanical properties of the femur, following treatment with anastrozole and letrozole in an experimental model of menopause[ol.2017.6596] | 
| Journal of Biomedical Materials Research | RAW 264.7 co-cultured with ultra-high molecular weight polyethylene particles spontaneously differentiate into osteoclasts: an in vitro model of periprosthetic osteolysis[10.1002/jbm.a.35912] | 
| Oncotarget | Mesenchymal stem cells inhibit RANK-RANKL interactions between osteoclasts and Th17 cells via osteoprotegerin activity.[pubmed:29137353] | 
| Asian Journal of Biomedical and Pharmaceutical Sciences | A Water Extract of Benefiting-Bone Capsule Improves Osteoporosis via Transcriptional and Translational Regulation of Key Factors in Notch and Wnt/???2-catenin Signaling Pathways in Ovariectomized Rats[ISSN 2249 – 622X] | 
| ACS Applied Materials and Interfaces | Enhanced Osseointegration of Porous Titanium Modified with Zeolitic Imidazolate Framework-8.[pubmed:28696091] | 
| Journal of?Clinical?Periodontology? | Peroxisome proliferator‐activated receptor γ plays dual roles on experimental periodontitis in rats[Pubmed:29574908] | 
| Journal of Functional Foods | Effect of long-term administration of mangiferin from on bone metabolism in ovariectomized rats[10.1016:j.jff.2018.04.048] | 
| Macromolecular?Bioscience | Strontium‐Substituted Hydroxyapatite‐Gelatin Biomimetic Scaffolds Modulate Bone Cell Response[Pubmed:29877029] | 
| Journal of Ethnopharmacology | Effects of water extract from epimedium on neuropeptide signaling in an ovariectomized osteoporosis rat model[Pubmed:29705515] | 
| International Journal of Molecular Medicine | Bu?Shen?Ning?Xin decoction suppresses osteoclastogenesis by modulating RANKL/OPG imbalance in the CD4+ T lymphocytes of ovariectomized mice[Pubmed:29717766] | 
| Journal of?Bone?and?Mineral?Metabolism | Allogeneic yet major histocompatibility complex-matched bone marrow transplantation in mice results in an impairment of osteoblasts and a significantly reduced?…[Pubmed:28766138] | 
| Journal of?Bone?and?Mineral?Metabolism? | Therapeutic effect of icariin combined with stem cells on postmenopausal osteoporosis in rats[Pubmed:28681147] | 
| Pharmacology | Effects of Amlodipine on Bone Metabolism in Orchidectomised Spontaneously Hypertensive Rats[Pubmed:29898457] | 
| Experimental and Therapeutic Medicine | Liraglutide exerts a bone?protective effect in ovariectomized rats with streptozotocin?induced diabetes by inhibiting osteoclastogenesis[Pubmed:29805533] | 
| Bone | The sole and combined effect of simvastatin and platelet rich fibrin as a filling material in induced bone defect in tibia of albino rats[Pubmed: 30208342] | 
| Bone?Research | NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts[Pubmed: 30455992] | 
| Bone | Development and characterization of supramolecular calcitonin assembly and assessment of its interactions with the bone remodelling process[Pubmed: 30797058] | 
| RSC?Advances | Biofunctionalization of decellularized porcine aortic valve with OPG-loaded PCL nanoparticles for anti-calcification[Doi: 10.1039/C9RA00408D] | 
| ANTICANCER RESEARCH | Promoter Methylation Down-regulates Osteoprotegerin Expression in Ovarian Carcinoma[Pubmed: 31092428] | 
| BIOSCIENCE REPORTS | IL-38 restrains inflammatory response of collagen-induced arthritis in rats via SIRT1/HIF-1α signaling pathway[Pubmed: 32347300] | 
| Oxid Med Cell Longev | Long-Term Administration of Abacavir and Etravirine Impairs Semen Quality and Alters Redox System and Bone Metabolism in Growing Male Wistar Rats[34373766] | 
| Biomed Pharmacother | Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis[Pubmed:35453007] | 
| Medicina (Kaunas) | Plasma Concentrations of New Biochemical Markers of Atherosclerosis in Patients with Dyslipidemia—A Pilot Study[Pubmed:35743980] | 
| Journal of Orthopaedic Translation | Exercised accelerated the production of muscle-derived kynurenic acid in skeletal muscle and alleviated the postmenopausal osteoporosis through the Gpr35?…[] | 


